Sicheng Tang (Associate Professor)
汤思成 国科温州研究院昝兴杰课题组岗位研究员
教育经历：
2013年获吉林大学材料化学学士学位(师从张晓安教授)，2018年获美国迈阿密大学化学博士学位(师从Francisco Raymo教授，诺奖得主Fraser Stoddart学生)。2018-2021年先后在美国天普大学和宾夕法尼亚州立大学做博士后。2021年任中国科学院大学温州研究所岗位研究员。共发表论文27篇，其中中科院一区11篇，包括Journal of the American Chemical Society、National Science Review、Nature Communications、ACS Sensors等。此外，还作为国家卫生研究院(NIH)和国家科学基金会(NSF)的主要研究员参与研究。
主要研究方向：
（1）基于oxazine的分子开关在细胞内pH检测、细胞标记以及超分辨荧光成像上的应用；
（2）功能性荧光分子在检测细胞内极性、粘度等微环境变化方面的应用；
（3）两亲性聚合物结构与其性质关系以及其包裹亲脂性有机分子在细胞成像中的应用
目前聚焦于：
（1）功能性荧光分子在药物递送方面的辅助应用以及；
（2）基于分子开关的智能响应型药物递送体系的构建及应用。
发表的论文：
1. "Hyperconjugation effect on fluorescence enhancement of biomimic disulfide substituted spirooxazine": S. Zhu, M. Li*, Y. Zhang, S. Tang, J. Yang, Y. Wang, L. Sun, L. Sheng, B. Yang, S. X. Zhang*, RSC Adv., 2013, 43, 19752-19755 IF: 3.070, 三区
2. "Electrochromic Switching and Microkinetic Behaviour of Oxazine Derivatives and Their Applications": S. Zhu, M. Li*, S. Tang, Y. Zhang, B. Yang, S. X. Zhang*, Eur. J. Org. Chem, 2014, 6, 1227–1235 IF: 2.889, 三区
3. "Photoactivatable BODIPYs Designed to Monitor the Dynamics of Supramolecular Nanocarriers": Y. Zhang, S. Swaminathan, S. Tang, J. Garcia-Amorós, M. Boulina, B. Captain*, J.D. Baker*, and F. M. Raymo*, J. Am. Chem. Soc., 2015, 137, 4709–4719 IF:14.612, 一区
4. "Supramolecular Nanoreactors for Intracellular Singlet-Oxygen Sensitization": S. Swaminathan, C. Fowley, E. R. Thapaliya, B. McCaughan, S. Tang, A. Fraix, B. Captain*, S Sortino*, J. F. Callan*, F. M. Raymo*, Nanoscale, 2015, 7, 14071–14079 IF: 6.895, 二区
5. "Energy-Transfer Schemes to Probe Fluorescent Nanocarriers and Their Emissive Cargo": E. R. Thapaliya, C. Fowley, B. Callan, S. Tang, Y. Zhang, J. F. Callan*, F. M. Raymo*, Langmuir, 2015, 31, 9557–9565 IF: 3.557, 二区
6. "Self-Assembling Nanoparticles of Amphiphilic Polymers for in Vitro and in VivoFRET Imaging": J. Garcia-Amorós, S. Tang, Y. Zhang, E. R. Thapaliya, F. M. Raymo*, Top. Curr. Chem., 2016, 370, 29–59 IF: 7.455, 二区
7. "Supramolecular Nanocarriers with Photoresponsive Cargo ": Y. Zhang, S. Tang, E. R. Thapaliya, F. M. Raymo*, Proc. SPIE, 2016, 97220C-1–6 IF:0.56, 无
8. "Synthesis in Living Cells with the Assistance of Supramolecular Nanocarriers": S. Shaban Ragab, E. R. Thapaliya, Y. Zhang, S. Tang, J. B. McMahan, S. Syed, B. Captain*, F. M. Raymo*, RSC Adv., 2016, 6, 32441–32445 IF: 3.070, 三区
9. "Supramolecular Delivery of Fluorescent Probes in Developing Embryos": Y. Zhang, E. R. Thapaliya, S. Tang, J. D. Baker*, F. M. Raymo*, RSC Adv., 2016, 6, 72756–72760 IF: 3.070, 三区
10. "Emission Color Tuning and White-Light Generation Based on Photochromic Control of Energy Transfer Reactions in Polymer Micelles": M. Bälter, S. Li, M. Morimoto, S. Tang, J. Hernando, G. Guirado, M. Irie, F. M. Raymo*, J. Andréasson*, Chem. Sci., 2016, 7, 5867–5871 IF: 9.346, 一区
11. "Structural Implications on the Properties of Self-Assembling Supramolecular Hosts for Fluorescent Guests": S. Tang#, B. Donaphon#, M. Levitus*, F. M. Raymo*, Langmuir, 2016, 32, 8676–8687 IF: 3.557, 二区
12. "Semiconductor Quantum Dots with Photoresponsive Ligands": L. Sansalone, S. Tang, Y. Zhang, E. R. Thapaliya, F. M. Raymo*, J. Garcia-Amorós*, Top. Curr. Chem., 2016, 374, 73-1–30 IF: 7.455, 二区
13. "A Photoswitchable Fluorophore for the Real-Time Monitoring of Dynamic Events in Living Organisms": Y. Zhang, S. Tang, L. Sansalone, J. D. Baker*, F. M. Raymo*, Chem. Eur. J., 2016, 22, 15027–15034 IF: 4.857, 二区
14. "Highlighting Cancer Cells with Halochromic Switches": S. Tang, Y. Zhang, E. R. Thapaliya, A. Brown, J. N. Wilson*, F. M. Raymo*, ACS Sensors, 2016, 2, 92-101 IF: 7.333, 一区
15. "Free-energy predictions and absorption spectra calculations for supramolecular nanocarriers and their photoactive cargo": A. Pietropaolo*, S. Tang, F. M. Raymo*, Nanoscale, 2017, 9, 4989-4994 IF: 6.895, 二区
16. "Supramolecular Delivery of Fluorescent Probes in Developing Embryos": Y. Zhang, E. R. Thapaliya, S. Tang, J. D. Baker*, F. M. Raymo*, Proc. SPIE, 2017, 100781A-1 IF:0.56, 无
17. "Probing the intracellular fate of supramolecular nanocarriers and their cargo with FRET schemes ": E. R. Thapaliya, C. Fowley, B. Callan, S. Tang, Y. Zhang, J. F. Callan*, F. M. Raymo*, Proc. SPIE, 2017, 100781B-1 IF:0.56, 无
18. "Highlighting Cancer Cells with Halochromic Switches": S. Tang, Y. Zhang, E. Thapaliya, A. Brown, J. N. Wilson*, F. M. Raymo*, Proc. SPIE, 2017, 1007814-1 IF:0.56, 无
19. "Photochemical Barcodes": S.Tang#, Y, Zhang#, P. Dhakal, L. Ravelo#, C. L. Anderson, K. M. Collins*, F. M. Raymo*, J. Am. Chem. Soc., 2018, 140, 4485-4488 IF:14.612, 一区
20. "Fluorescence activation with switchable oxazines": Y. Zhang, S. Tang, E. R. Thapaliya, L. Sansalone, F. M. Raymo*, Chem. Commun, 2018, 54, 8799. IF: 5.996, 二区
21. "A Photoactivatable Far-Red/Near-Infrared BODIPY To Monitor Cellular Dynamics in Vivo": L. Sansalone, S. Tang, J. Garcia-Amorós, Y. Zhang, S. Nonell, J. D. Baker*, B. Captain*, F. M. Raymo*. ACS Sensors 2018, 3, 1347-1353. IF: 7.333, 一区
22. "Far-Red Photoactivatable BODIPYs for the Super-Resolution Imaging of Live Cells": Y. Zhang, K. Song, S. Tang, L. Ravelo, J. Cusido, C. Sun, H. F. Zhang*, F. M. Raymo*. J. Am. Chem. Soc. 2018, 140, 12741–12745. IF:14.612, 一区
23. "An all-photonic full color RGB system based on molecular photoswitches": G. Naren, C. Hsu, S. Li, M. Morimoto, S. Tang, J. Hernando, G. Guirado, M. Irie, F. M. Raymo*, H. Sundén*, J. Andréasson*, Nat. Commun. 2019, 10:3996, 1-7. IF: 12.121, 一区
24. "Photopotentiation of the GABAA receptor with caged diazepam": L. Sansalone, J. B. Prince, S. Tang, B. Captain*, D. D. Mott*, F. M. Raymo*. PNAS. 2019, 201902383. IF: 9.412 一区
25. "Far-red photoactivatable BODIPYs for the super-resolution imaging of live cells": Y. Zhang, S. Tang, L. Ravelo, J. Cusido, F. M. Raymo*, Methods in Enzymology. 2020, 640, 131-147. IF: 2.002 四区
26. "When aggregation-induced emission meets protein aggregates": S. Tang#, S. Ye#, X. Zhang*, National Science Review. 2021, nwab013. IF: 16.693, 一区
27. "Direct visualization and profiling of protein misfolding and aggregation in live cells": S. Tang#*, W. Wang#, X. Zhang*, Curr Opin Chem Biol, 2021, 64, 116-123. IF: 9.689, 二区